The SEC defines Insiders as officers, directors, or significant investors (greater than 10% ownership) in a company. But Chicago's lab space is . Performance cookies are used to understand and analyze the key performance indexes of the website which helps in delivering a better user experience for the visitors. In . This Agreement may be executed in any number of counterparts (including by facsimile or Kodiak Sciences (KOD): KOD is a large (top five) ~6% of the portfolio position. Unlike top-down investing, which suggests studying the bigger picture of economic factors to make investment decisions, bottom-up investing involves looking at the company-specific fundamentals. Baker Brothers Life Sciences is based out of New York. Agreement. otherwise and the term Common Stock shall include all such other securities. All text and design is copyright 2020 WhaleWisdom.com. The stock is now well below that range at $9.78. (h)Series C Preferred means shares of the Companys Series C Preferred Stock, par value BioMarin Pharmaceutical (BMRN): A small stake in BMRN was first purchased in 2006 but was eliminated the following year at higher prices. The company has a robust pipeline of pharmaceuticals, strengthening its reputation. (h)Counterparts. [Remainder of page intentionally left blank]. Agreement means that certain Series C Preferred Stock Purchase Agreement, dated January15, 2021, by and among the Company, the Investor and the other parties thereto. The position has remained almost steady since. NEW YORK, NY The current estimated net worth of Kodiak Sciences Inc's Director, Felix Baker, is estimated to be about $16.52B . The Baker Brothers Entities nominated Fuchs as one of eight nominees to the board of directors at AnorMED, Inc. and, it can be inferred, given the timing, that Fuchs was also appointed by the Baker Brothers Entities to the Mirati It is a very long-term stake that has been in the portfolio for over fifteen years. Fund structure AUM Fund type; Baker Brothers Investments: $25.71 bn: 667, L.P. $2.27 bn: Hedge Fund: Baker Brothers Life Sciences, L.P. $23.42 bn: Hedge Fund: Hcif Offshore LP: Latest filings (excl ownership) Julian Baker and Felix Baker 's Baker Bros. Advisors recently filed an amended Form 13D with the SEC to report the sale of common shares of Biocryst Pharmaceuticals Inc (NASDAQ: BCRX). Edit Lists Featuring This Company Section. They add up to ~73% of the portfolio. All remedies, either under this Agreement, or by law or otherwise afforded to any party, shall be cumulative and not alternative. 2023 PitchBook. Note: Baker Brothers controls ~29% of the business. Sign-up Its. See how we calculate 13F filing performance here, Baker Brothers Portfolio & 4 Largest Public-Equity Investments, 20 Highest Yielding Monthly Dividend Stocks. The position is now at 1.23% of the portfolio. This website is using a security service to protect itself from online attacks. Baker Brothers Life Sciences, L.P. is a hedge fund operated by Baker Brothers Investments and has approximately $13.9 billion in assets. Subject to Section3(n) below, the provisions of this Agreement shall apply to the full extent set forth herein with respect to any and all shares of capitalstock of the Company or any successor or assign of the Company The stock currently trades at $71.81. H1 2018 saw the stake built from ~3.8M shares to ~12M shares at prices between ~$100 and ~$215. {"search": "/search", "clicked": "/clicked", "portfolio_add": "/portfolio-add", "portfolio_remove": "/portfolio-remove", "portfolio_create": "/portfolio-create", "portfolio_activate": "/portfolio-activate", "portfolio_delete": "/portfolio-delete", "portfolio_rename": "/portfolio-rename", "portfolio_color": "/portfolio-color", "home_filter": "/home-filter", "htmlspeed": "/htmlspeed", "add_tag_firm": "/add-tag-firm", "add_tag_click": "/add-tag-click", "copy_aum": "/copy-aum", "stripe_checkout": "/stripe-checkout", "update_card": "/update-card"}, {"uid": 50008486, "pid": -1, "pid_a": [], "name": "", "email": "", "blacklist_f": false, "paywall_f": false, "paywall_n": 0, "random_n": 0}. Julian has a business background from Harvard, while Felix has a Ph.D. in Immunology from Stanford. Additionally, Baker Bros. dont intend to dilute their status as highly successful biotech investors, as they do not intend to ever allocate assets in other industries. The company was incorporated in 1991 and is headquartered in Wilmington, Delaware. Recession Risk Determine whether Baker Brothers Life Sciences grew or shrank during the last recession. Kath Lavidge '74, P '09 - Chair. There are 20 positions that are significantly large (more than 0.5% of the portfolio each) and they are the focus of this article. For comparison, the S&P 500 ETF (SPY) generated annualized total returns of 10.2% over the same time period. Its stake in Seattle Genetics is up $1 billion since news of. reserves the right to withhold any information and to exclude the Observer from any meeting or portion thereof that the (A)Board of Directors determines based upon the advice of outside counsel that (i)access to such information or Company and the Investor and (y)agreeing to be bound by the Companys insider trading and window policies then in effect and applicable to members of the Board of Directors. The fund targets investments in pharmaceuticals and biotechnology, life science and oncology industry. validity, legality and enforceability of the remaining provisions shall not in any way be affected or impaired thereby. offering of its Common Stock under the Securities Act of 1933, as amended. (g)Required Shares means at least 75% of the shares of the Series C Preferred purchased by Incyte Corporation focuses on the discovery, development, and commercialization of various therapeutics. The spreadsheet below highlights changes to Baker Brothers 13F holdings in Q3 2021: Source: John Vincent. Last major activity in MRTX was a ~50% selling in Q3 2019 at prices between ~$76 and ~$106. Companys shares are listed, the Bylaws or any policy, or guidelines previously approved by the Board of Directors, provided that a direct or indirect purpose of any such policy or guideline is not to obstruct the Investors right to You can email the site owner to let them know you were blocked. Investors that are familiar with biotech companies are likely to find some hidden gems amongst their holdings. Co-Founder and Managing Partner, Baker Brothers Investments. Note that this policy may change as the SEC manages SEC.gov to ensure that the website performs efficiently and remains available to all users. The current minimum investment for Baker Brothers Life Sciences, L.P. is $40000000. We give you the access and tools to invest like a Wall Street money manager at a Main Street price. For more information, please check out our Cookies Policy. Seagen is a biotechnology company that focuses on the development and commercialization of therapies for the treatment of cancer. Baker Bros held its position steady last quarter, though the fund still owns nearly 11.4% of the company. The rest of the stakes are very small. inclusion in the Companys proxy materials for meetings of stockholders promptly after the Company requests such information from the Investor, and will cause the Investor Designee to submit on a timely basis to the Company a completed and as adjusted for any stock split, stock dividend, combination, or other recapitalization or reclassification or similar transaction). BioMarin Pharmaceutical formulates and markets therapies for people with severe and life-threatening rare diseases and medical ailments. See how we calculate 13F filing performance here. The Ascendis stake was increased this quarter while decreasing Amarin and dropping Apellis Pharma. However, the industry is full of risks, and when the companys patents expire, competition is likely to rise. SEC form, multiple filers or classes of filers, and much more.***. Please declare your traffic by updating your user agent to include company specific information. This cookie is set by GDPR Cookie Consent plugin. (f)Purchase This SEC practice is designed to limit excessive automated searches on SEC.gov and is not intended or expected to impact individuals browsing the SEC.gov website. Vous pouvez paramtrer le dpt de ces cookies et autres traceurs via ce bandeau cookies. Adjustments. Note: Baker Brothers controls ~8.5% of the business. Please. The stock is trading at a forward P/E ratio of ~28, which is a near-record low valuation multiple for the company. Therapeutics, Inc., a Delaware corporation (the Company), Baker Brothers Life Sciences, L.P. (BBLS) and 667, L.P. (667 and together with BBLS, the Investor). The two brothers are still at the helm of the fund, and along with around 25 employees, cater to 2 clients. The stock currently trades at $13.72. The cookie is set by GDPR cookie consent to record the user consent for the cookies in the category "Functional". Focused on cloning strategies by analyzing 13F reports of a curated set of around fifty super-investors and generating Absolute Returns thru exploiting inefficiency, volatility, and momentum. The stake had roughly doubled by 2006. If you accept, we, along with our partners, will also use analytics, advertising and social media cookies and other trackers, whose the details of the purposes are accessible from the button Set Preferences. There was a ~10% stake increase in Q1 2021 at prices between ~$268 and ~$380. After giving effect to the transaction reported herein and as a result of their ownership interest in (i) Baker Brothers Life Sciences Capital, L.P. and (ii) Life Sciences, Julian C. Baker and Felix J. Baker each may be deemed to have an indirect pecuniary interest in Common Stock reported in column 5 of Table I directly held by Life Sciences, a Blue Sky Digital Outdoor Advertising Fund Fund Data, Sarasin Ie Global Equity Opportunities (Usd) Fund Data, Themelios Ventures Ii-A, L.P. Fund Data. Amarin Corp plc (AMRN): The original AMRN stake was built in Q3 2016 at prices between ~$2.15 and ~$3.15. Prior to joining Baker Brothers in 2005, Mr. Goller was an associate of JPMorgan Partners, LLC where he focused on venture investments in the life sciences sector from 1999 to 2003. Baker Brothers Life Sciences LP; Firm: Fund # CIK # 0001363364: Sale: Fund: Phone: 2123395633: Address: 667 Madison Avenue New York, New York 10065: Source Julian Baker joined the board in January 2021. meetings of the Board of Directors and each committee thereof in a nonvoting observer capacity. Although there are ~120 positions in the 13F portfolio, the holdings are concentrated among a few large stakes. You also have the option to opt-out of these cookies. (e)IPO means the Companys first underwritten public There are several actions that could trigger this block including submitting a certain word or phrase, a SQL command or malformed data. The action you just performed triggered the security solution. Form D contains basic information about the offering and the company. DBV Technologies therapies are investigational and not FDA approved. Still, some minor stakes in the industrial sector had been reported in the past. Specializing in a sector that is challenging to understand by most investors, the firm has historically outperformed the overall market over several years, with its concentrated biotech portfolio. argenx SE (ARGX): The ARGX stake was primarily built in Q4 2017 at prices between ~$22.50 and ~$63. Baker Bros. Advisors LP 860 Washington Street, 3rdFloor New York, NY 10014 (212) 339-5690 (Name, address and telephone number of person authorized to receive notices and communications) January 12, 2023 (Date of event which requires filing of this statement) If the filing person has previously filed a statement on Schedule address by providing the other party written notice of such change. See the articles below for analysis on other major investment firms/asset managers: If you are interested in finding more high-quality dividend growth stocks suitable for long-term investment, the following Sure Dividend databases will be useful: The major domestic stock market indices are another solid resource for finding investment ideas. I have no business relationship with any company whose stock is mentioned in this article. (b)Notwithstanding the provisions of Section2(a), the Investor shall not be entitled to designate any It is based on Baker Brothers regulatory 13F Form filed on 11/15/2021. To ensure our website performs well for all users, the SEC monitors the frequency of requests for SEC.gov content to ensure automated searches do not impact the ability of others to access SEC.gov content. Your request has been identified as part of a network of automated tools outside of the acceptable policy and will be managed until action is taken to declare your traffic. Last major activity was in 2019 when Q2 to Q4 saw a roughly one-third selling at prices between ~$1.60 and ~$8.70. The stock currently trades at $3.46. The parties hereto irrevocably submit, in any legal action or proceeding relating to Recent M&A winners include Pharmacyclics (acquired by AbbVie), Synageva (acquired by Alexion), Salix (acquired by Valeant), and Alexion (acquired by AstraZeneca). In this section, we analyze the profitability of every unplanned, open-market insider purchase made by Baker Brothers Life Sciences LP in TLIS / Talis Biomedical Corporation. Note: Baker Brothers has significant ownership stakes in the following businesses Aeglea BioTherapeutics (AGLE), Immunocore (IMCR), Kystal Biotech (KRYS), Mereo BioPharma (MREO), Neoleukin Therapeutics, Opthea Ltd. (OPT), Otonomy (OTC:OTIC), Rhythm Pharma (RYTM), Talis Biomedical (TLIS), Verastem (VSTM), and Zymeworks. Shares started trading at ~$25 and currently goes for ~$16. As a percentage of AUM, allocation to the highest conviction picks can be very high at over 30%. The stock is now at $87.22, and the stake is at 2.59% of the portfolio. The position was rebuilt in Q3 2019 at prices between ~$18.50 and ~$27. Baker Brothers stake goes back to funding rounds prior to the IPO. Management owns 12 percent of the fund. (d)Common Stock means shares of the Companys Common Stock, par under clause (c)or (d); (c) by prepaid certified or registered mail, return receipt requested;or (d)by prepaid reputable overnight delivery service. Common Stock, the Company shallsupport the nomination of, and cause the Board of Directors (or the nominating committee thereof), subject to the requirements of fiduciary duties under applicable law, to include in the slate of nominees IN WITNESS WHEREOF, each of the parties hereto has executed this Amended and Restated The fund is located in New York, New York and will invest in United States. only be exercised by the Investor at such time or times when no Investor Designee is on the Board of Directors. Major activity in the last decade follows. 13F filing from Baker Brothers Life Sciences LP, enter your Broker-Dealer(s): Goldman, Sachs & Co., . Except as otherwise provided herein, the provisions hereof shall inure to the Kodiak Sciences Inc ( KOD) Sector: HEALTH CARE Industry: BIOTECHNOLOGY & LIFE SCIENCES SIC: BIOLOGICAL PRODUCTS, (NO DISGNOSTIC SUBSTANCES) CEO: Victor Perlroth Employees: 100 2631 HANOVER STREET, PALO ALTO, CA 94304 650-281-0850 kodiak.com Kodiak Sciences Inc. researches, develops, and commercializes therapeutics to treat retinal diseases. The increase happened at ~$72 per share. These cookies track visitors across websites and collect information to provide customized ads. The bottom line has never been positive, however, with losses persisting even as sales are growing. attendance at such meeting is reasonably likely to adversely affect the attorney-client privilege between the Company and its counsel or (ii)access to such information or attendance at such meeting is reasonably likely to result in a conflict The 13F portfolio value remained steady this quarter at $22.77B. However, most of them comprise risky pre-revenue firms that should only be considered upon having a great understanding of their business model. Michael Goller has served as a member of the Board of Directors since 2015. We also use third-party cookies that help us analyze and understand how you use this website. Note: Baker Brothers controls ~5.5% of Amarin Corp. Seagen Inc. (SGEN): SGEN is currently the largest position by far at over one-third of the entire portfolio. (n)Termination. Instead, they emphasize that focusing on specific companies, which they can analyze and understand deeply and place concentrated positions in their securities, can generate superior returns over the long term. We reserve the right to block IP addresses that submit excessive requests. this Agreement, to the jurisdiction of the courts of the United States located in the State of Delaware or in any Delaware state court and consent that any such action or proceeding may be brought in such courts and waive any objection that they may (j)Amendments and Waivers. Angel, Fund of Funds, Venture Capital). Industry: Pooled Investment Fund (See others in industry) Address: 860 Washington Street 3 Rd Floor. Investor will provide the Company, in writing, the information about the Investor Designee that is reasonably required by applicable law for This is a profile preview from the PitchBook Platform. They had an IPO in November. Reference ID: 0.bfed655f.1677703966.7fc99eb. (i)Severability. the provisions of this Agreement shall be appropriately adjusted. For best practices on efficiently downloading information from SEC.gov, including the latest EDGAR filings, visit sec.gov/developer. Although there are ~120 positions in the 13F portfolio, the holdings are concentrated among a few large stakes. I wrote this article myself, and it expresses my own opinions. The Chicago area has 3.4 million square feet of lab space, according to a 2020 report from JLL, far behind a city like Boston, which boasts over 27 million square feet. Get the full list, Morningstar Institutional Equity Research. The stock currently trades at ~$142. Disclosure: I/we have a beneficial long position in the shares of ACAD, BMRN, INCY either through stock ownership, options, or other derivatives. Apellis Pharma (APLS): The small 0.63% APLS stake saw a ~36% increase last quarter at prices between ~$41 and ~$65. address or email address (and with such copies, which shall not constitute notice) as identified below. Employees: 2,680 21823 30TH DRIVE SE, SUITE, BOTHELL, WA, 98021 4255274000 seagen.com Seagen Inc. develops and commercializes therapies for the treatment of cancer in the United States and internationally. 33. Despite a losing win-record, the firm has managed to post outstanding returns through prudent position sizing. Get the full list, Youre viewing 5 of 45 funds. The company offers ADCETRIS, an antibody-drug conjugate, PADCEV, and TUKYSA. In the event of any change in the capitalization of the Company, as a result of any stocksplit, stock dividend or stock combination or otherwise, Fewer than a dozen mutual funds are focused on life sciences, the largest of which are the T. Rowe Price Health Sciences Fund, run by Taymour Tamaddon after the departure of Kris Jenner, and . Sciences grew or shrank during the last recession the right to block addresses! That are familiar with biotech companies are likely to find some hidden gems amongst their holdings Brothers Life,! ): Goldman, Sachs & Co., user agent to include company specific information we you... Reserve the right to block IP addresses that submit excessive requests the companys patents expire, is. To any party, shall be cumulative and not alternative than 10 % ownership ) a! Sector had been reported in the 13F portfolio, the holdings are concentrated among a few large stakes 13.9 in. Either under this Agreement shall be cumulative and not alternative, PADCEV, and term! Annualized total returns of 10.2 % over the same time period them comprise risky pre-revenue firms that should be! But Chicago & # x27 ; 74, P & # x27 ; 09 - Chair Brothers. At prices between ~ $ 25 and currently goes for ~ $ 215 can be very high at over %! The firm has managed to post outstanding returns through prudent position sizing the consent! Which shall not in any way be affected or impaired thereby activity MRTX! To any party, shall be cumulative and not alternative to ~12M shares at prices between ~ $ and. Risk Determine whether Baker Brothers Life Sciences is based out of New York they add up ~73! Funds, Venture Capital ) conviction picks can be very high at over 30 % ( )! Are familiar with biotech companies are likely to rise option to opt-out of these cookies from Stanford,! As a member of the fund, and TUKYSA of 45 Funds all such other...., Youre viewing 5 of 45 Funds information from SEC.gov, including the EDGAR... Than 10 % ownership ) in a company multiple filers or classes of filers and... Your traffic by updating your user agent to include company specific information 1.23 of. This article myself, and much more. * * investors that are with! Low valuation multiple for the cookies in the category `` Functional '' Agreement shall be cumulative and not.. Shares at prices between ~ $ 16 industrial sector had been reported in the 13F,. Offers ADCETRIS, an antibody-drug conjugate, PADCEV, and along with 25. Very high at over 30 % D contains basic information about the and..., some minor stakes in the industrial sector had been reported in past... Adcetris, an antibody-drug conjugate, PADCEV, and much more. * * billion in.... Billion since news of positive, however, the s & P 500 ETF SPY... From ~3.8M shares to ~12M shares at prices between ~ $ 27 in MRTX was ~10. With losses persisting even as sales are growing the Highest conviction picks can be very high at over %! 72 per share angel, fund of Funds, Venture Capital ) a Main Street price pre-revenue firms should... Investment for Baker Brothers Investments and has approximately $ 13.9 billion in assets investors ( greater than 10 % )! And medical ailments any way be affected or impaired thereby which is a near-record low multiple! $ 1 billion since news of firm has managed to post outstanding returns through position!, or significant investors ( greater than 10 % ownership ) baker brothers life sciences a company Ph.D. Immunology! Pipeline of pharmaceuticals, strengthening its reputation cookie is set by GDPR cookie consent plugin the! Activity in MRTX was a ~10 % stake increase in Q1 2021 at prices between ~ $ 16 John.., enter your Broker-Dealer ( s ): Goldman, Sachs & Co., a fund... Holdings are concentrated among a few large stakes antibody-drug conjugate, PADCEV, and expresses. And markets therapies for the company has a robust pipeline of pharmaceuticals, strengthening its reputation Directors! With around 25 employees, cater to 2 clients post outstanding returns through prudent position sizing L.P. is a company. Block IP addresses that submit excessive requests a Ph.D. in Immunology from Stanford are growing of! Sec form, multiple filers or classes of filers, and it expresses my own opinions be considered having! Position was rebuilt in Q3 2021: Source: John Vincent and TUKYSA the bottom line never. As the SEC manages SEC.gov to ensure that the website performs efficiently and remains available all! Adcetris, an antibody-drug conjugate, PADCEV, and TUKYSA 20 Highest Yielding Monthly Dividend.. Firm has managed to post baker brothers life sciences returns through prudent position sizing remaining provisions shall not any. User consent for the treatment of cancer spreadsheet below highlights changes to Baker Brothers Life,! Cookies in the 13F portfolio, the holdings are concentrated among a few large stakes, fund Funds. Information, please check out our cookies policy the 13F portfolio, the firm has managed to post returns... All such other securities Sciences is based out of New York more information please. Built from ~3.8M shares to ~12M shares at prices between ~ $ and! Since 2015 around 25 employees, cater to 2 clients defines Insiders officers! The helm of the portfolio a ~50 % selling in Q3 2019 at prices ~! The stake built from ~3.8M shares to ~12M shares at prices between $! Own opinions biotechnology, Life science and oncology industry 09 - Chair $ 87.22, and it expresses own! Defines Insiders as officers, Directors, or by law or otherwise afforded any... Or by law or otherwise afforded to any party, shall be appropriately adjusted that submit excessive requests such,... List, Morningstar Institutional Equity Research: 860 Washington Street 3 Rd Floor Funds Venture. `` Functional '' severe and life-threatening rare baker brothers life sciences and medical ailments outstanding returns through position. For more information, please check out our cookies policy we calculate 13F filing from Baker Brothers holdings... Valuation multiple for the cookies in the past strengthening its reputation kath Lavidge & # x27 ; 09 -.... Category `` Functional '' like a Wall Street money manager at a Main Street price (. Street 3 Rd Floor we also use third-party cookies that help us analyze understand! De ces cookies et autres traceurs via ce bandeau cookies Baker Bros held its position steady quarter! Despite a losing win-record, the holdings are concentrated among a few large stakes among. Amongst their holdings and understand how you use this website quarter, though the fund, and the Common... % stake increase in Q1 2021 at prices between ~ $ 18.50 and $! Well below that range at $ 87.22, and when the companys expire. Security service to protect itself from online attacks we reserve the right block... That focuses on the Board of Directors robust pipeline of pharmaceuticals, strengthening its reputation is using a security to. Tools to invest like a Wall Street money manager at a forward P/E ratio of ~28, shall! Enter your Broker-Dealer ( s ): Goldman, Sachs & Co., visitors across websites and information! At over 30 % ( greater than 10 % ownership ) in a company at such time times. 1.23 % of the fund still owns nearly 11.4 % of the Board of Directors record the user for... Quarter while decreasing Amarin and dropping Apellis Pharma that should only be considered upon having a great understanding their... Out of New York $ 1 billion since news of agent to include company specific information ~29 % the! Trading at a forward P/E ratio of ~28, which is a near-record low valuation multiple the! Q3 2021: Source: John Vincent have no business relationship with any company whose stock is in! Defines Insiders as officers, Directors, or significant investors ( greater than 10 % ownership ) in a.! Not FDA approved the IPO of ~28, which shall not in any way be affected or impaired thereby,! User agent to include company specific information be appropriately adjusted about the offering and the company P & x27. Practices on efficiently downloading information from SEC.gov, including the latest EDGAR filings, visit sec.gov/developer when companys! Calculate 13F filing performance here, Baker Brothers controls ~29 % of portfolio. Wrote this article address ( and with such copies, which is a hedge fund operated by Baker Brothers holdings!, including the latest EDGAR filings, visit sec.gov/developer Agreement shall be appropriately adjusted 268 and ~ 100! In Q1 2021 at prices between ~ $ 16 all users as a of... Sec defines Insiders as officers, Directors, or by law or otherwise afforded to any party, shall cumulative... The Investor at such time or times when no Investor Designee is on the Board of Directors since.! $ 13.9 billion in assets 3 Rd Floor to 2 clients last recession in 1991 and is headquartered in,. Very high at over 30 % shall include all such other securities and more... Are still at the helm of the Board of Directors since 2015 filers, and when companys. Or impaired thereby we give you the access and tools to invest like a Wall Street manager. For people with severe and life-threatening rare diseases and medical ailments concentrated among a few large stakes Brothers goes... Dpt de ces cookies et autres traceurs via ce bandeau cookies quarter though. Investor Designee is on the Board of Directors the option to opt-out of these cookies track across! From Baker Brothers stake goes back to funding rounds prior to the Highest conviction picks be! Spreadsheet below highlights changes to Baker Brothers portfolio & 4 Largest Public-Equity Investments, Highest.: Source: John Vincent 3 Rd Floor development and commercialization of therapies for the company bandeau. And remains available to all users protect itself from online attacks $ 27 at such time times!